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You may be able to take Tadalafil at a lower dose even if you already take certain drugs or have pre-existing conditions, so always disclose your full medical history. If you use nitrates either medically, for example, if you have angina, or you use recreational nitrate-based drugs, Tadalafil is NOT SUITABLE. This is because PDE-5 inhibitors increase the effect of nitrates and may lower your blood pressure.
Generic medications have the same active ingredient as their branded versions but are available on the market at a much lower price. Manufacturers of generic medicines have to show that the medicines are equally effective, that is, they have the same strength, quality, stability and efficacy. Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product before they can be sold - i.e. they offer the same quality, strength, stability and effectiveness. Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.
However, using this medication as part of a comprehensive treatment that may include couples therapy can be more helpful. Cialis and Viagra have different active ingredients in them that make them work. So, the doses of Cialis and Viagra are not related and you can’t compare the number of mg to figure out which might be more effective (e.g. 20mg of Viagra wouldn’t be the same as 20mg of Cialis). However, having pulmonary hypertension during pregnancy may cause complications or medical problems such as heart failure, and stroke in both mother and baby.
Since this date, other manufacturers have been able to produce a generic version of Cialis called Tadalafil. If you experience any serious side effects, go to A&