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Peak concentration in the blood is reached after two hours for tadalafil and about one hour for sildenafil. As such, we always suggest taking medication about an hour or two before sexual activity. The time it takes for the drug to function will vary between patients, so use prior experience as a guide.

In some cases, it may be possible to buy these medications online. Sildenafil is a great option for those who want to take ED medications as-needed. The medication starts working in as little as 30 minutes and remains active for 4 to 6 hours. Alternative treatments for ED include tablets such as Cialis&nbsp